The mesoSPIM (mesoscale selective plane illumination microscopy) project creates open-hardware microscopy platforms for imaging cleared tissue.
mesoSPIM features
Compatible with all clearing methods, simple and quick sample mounting and exchange, reduced shadowing artifacts and many more…
Isotropy across large FOVs
The mesoSPIM is an axially scanned light-sheet microscope (ASLM) for uniform z-resolution across the FOV.
Image large Samples
Fits a whole mouse CNS with 52 x 52 x 102 mm travel range - a larger sample volume than any other available light-sheet microscope.
Meetings and Workshops
Members of the mesoSPIM initiative organize a variety of workshops for the community.
Find a mesoSPIM near you.
Currently, there are more than 20 mesoSPIM setups in operation around the world.